Artvigil: Enhance Wakefulness and Cognitive Performance
| Product dosage: 150 mg | |||
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Synonyms | |||
Artvigil is a prescription medication containing Armodafinil, the R-enantiomer of Modafinil, designed to promote wakefulness in individuals with excessive sleepiness associated with narcolepsy, obstructive sleep apnea, or shift work sleep disorder. It functions by altering the natural chemicals (neurotransmitters) in the brain area that controls sleep and wakefulness, offering a targeted approach to managing sleep-wake cycle disruptions without the jitteriness associated with traditional stimulants. Approved by regulatory authorities, Artvigil provides a clinically validated option for improving alertness and supporting cognitive function under medical supervision.
Features
- Active ingredient: Armodafinil (150 mg per tablet)
- Form: Oral tablet
- Mechanism: Selective wakefulness-promoting agent with low abuse potential
- Half-life: Approximately 15 hours
- Bioavailability: High oral absorption, not affected by food
- Prescription status: Schedule IV controlled substance
Benefits
- Promotes sustained wakefulness and reduces excessive daytime sleepiness
- Enhances focus, concentration, and cognitive performance in sleep-deprived individuals
- Helps maintain alertness during night shifts or irregular work schedules
- Supports improved productivity and mental acuity with once-daily dosing
- Minimizes the crash or rebound fatigue common with traditional stimulants
- Non-amphetamine mechanism reduces risk of hyperactivity or euphoria
Common use
Artvigil is primarily prescribed for the treatment of excessive sleepiness associated with diagnosed medical conditions such as narcolepsy, obstructive sleep apnea (OSA) (as adjunct therapy to continuous positive airway pressure), and shift work sleep disorder. It is used off-label in some cases for attention deficit hyperactivity disorder (ADHD), fatigue related to multiple sclerosis, and depression, though these uses require careful medical evaluation and are not FDA-approved indications.
Dosage and direction
The standard recommended dose for Artvigil is 150 mg taken orally once daily in the morning for narcolepsy or OSA, or approximately one hour prior to the start of a work shift for shift work sleep disorder. It may be taken with or without food. Dosage adjustments may be necessary for patients with severe hepatic impairment, in which case a reduced dose of 50 mg is advised. Do not crush, chew, or break the tablet; swallow whole with water. Always follow the specific dosing instructions provided by your healthcare provider.
Precautions
- Use Artvigil under strict medical supervision; do not self-adjust the dose.
- Avoid alcohol, as it may exacerbate side effects or reduce effectiveness.
- Not recommended for use in patients with a history of left ventricular hypertrophy or mitral valve prolapse.
- Use with caution in patients with a history of psychosis, depression, or mania, as it may exacerbate underlying symptoms.
- May impair ability to drive or operate machinery; assess tolerance before engaging in hazardous activities.
- Regular monitoring of blood pressure and heart rate is advised during treatment.
- Not intended for use in pediatric patients under 17 years of age.
Contraindications
Artvigil is contraindicated in individuals with known hypersensitivity to Armodafinil, Modafinil, or any component of the formulation. It should not be used in patients with a history of symptomatic cardiovascular disease such as unstable angina, recent myocardial infarction, or significant arrhythmias. Use is also contraindicated in those with a history of drug abuse or addiction without careful risk-benefit assessment.
Possible side effect
Common side effects may include headache, nausea, dizziness, insomnia, anxiety, dry mouth, and diarrhea. Less frequently, patients may experience palpitations, increased blood pressure, blurred vision, or rash. Serious but rare side effects include Stevens-Johnson syndrome, angioedema, multiorgan hypersensitivity reactions, or psychiatric symptoms such as agitation, confusion, or hallucinations. Report any persistent or severe side effects to a healthcare professional immediately.
Drug interaction
Artvigil may interact with several medications, including cytochrome P450 3A4 inducers or inhibitors. It can reduce the effectiveness of hormonal contraceptives (e.g., birth control pills), necessitating alternative non-hormonal contraception during and for one month after treatment. Concurrent use with monoamine oxidase inhibitors (MAOIs) is not recommended. Artvigil may increase levels of drugs such as diazepam, phenytoin, or warfarin. Always inform your doctor of all medications, supplements, or herbal products you are taking.
Missed dose
If a dose is missed, take it as soon as remembered unless it is close to the time for the next scheduled dose. In that case, skip the missed dose and resume the regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects.
Overdose
Symptoms of overdose may include insomnia, restlessness, confusion, agitation, tachycardia, hypertension, or gastrointestinal distress. In case of suspected overdose, seek immediate medical attention or contact a poison control center. Treatment is supportive and may include symptomatic management; there is no specific antidote for Armodafinil overdose.
Storage
Store Artvigil at room temperature (20–25°C or 68–77°F), in a tightly closed container, away from light, moisture, and heat. Keep out of reach of children and pets. Do not use beyond the expiration date printed on the packaging.
Disclaimer
This information is for educational purposes only and does not constitute medical advice. Artvigil is a prescription medication and should be used only under the guidance of a qualified healthcare professional. Individual responses may vary, and not all uses or precautions may be covered here. Always consult your doctor for personalized recommendations and to discuss potential risks and benefits based on your medical history.
Reviews
Clinical studies and user reports indicate that Artvigil is generally well-tolerated and effective for improving wakefulness and cognitive function in indicated conditions. Many users note significant improvements in alertness and productivity, though individual experiences with side effects such as headache or insomnia may vary. Long-term satisfaction often depends on appropriate dosing and adherence to medical guidance.