Ciprodex Ophthalmic Solution: Potent Dual-Action Ocular Infection Control
| Product dosage: 250mg | |||
|---|---|---|---|
| Package (num) | Per pill | Price | Buy |
| 90 | $0.45 | $40.16 (0%) | 🛒 Add to cart |
| 120 | $0.37 | $53.54 $44.17 (18%) | 🛒 Add to cart |
| 180 | $0.30 | $80.31 $54.21 (33%) | 🛒 Add to cart |
| 360 | $0.22
Best per pill | $160.63 $79.31 (51%) | 🛒 Add to cart |
| Product dosage: 500mg | |||
|---|---|---|---|
| Package (num) | Per pill | Price | Buy |
| 60 | $0.72 | $43.17 (0%) | 🛒 Add to cart |
| 90 | $0.55 | $64.75 $49.19 (24%) | 🛒 Add to cart |
| 120 | $0.46 | $86.34 $55.22 (36%) | 🛒 Add to cart |
| 180 | $0.38 | $129.51 $68.27 (47%) | 🛒 Add to cart |
| 270 | $0.32 | $194.26 $86.34 (56%) | 🛒 Add to cart |
| 360 | $0.29
Best per pill | $259.01 $104.41 (60%) | 🛒 Add to cart |
| Product dosage: 750mg | |||
|---|---|---|---|
| Package (num) | Per pill | Price | Buy |
| 30 | $1.97 | $59.23 (0%) | 🛒 Add to cart |
| 60 | $1.39 | $118.46 $83.33 (30%) | 🛒 Add to cart |
| 90 | $1.18 | $177.69 $106.42 (40%) | 🛒 Add to cart |
| 120 | $1.09 | $236.93 $130.51 (45%) | 🛒 Add to cart |
| 180 | $0.99 | $355.39 $177.69 (50%) | 🛒 Add to cart |
| 360 | $0.88
Best per pill | $710.78 $318.24 (55%) | 🛒 Add to cart |
Synonyms | |||
Ciprodex Ophthalmic Solution is a prescription sterile, topical otic and ophthalmic suspension combining the broad-spectrum fluoroquinolone antibiotic ciprofloxacin with the potent corticosteroid anti-inflammatory agent dexamethasone. It is specifically formulated for the treatment of superficial ocular infections where both antimicrobial and anti-inflammatory actions are clinically indicated. This combination offers physicians a reliable option for managing bacterial conjunctivitis and other external eye infections with an inflammatory component, providing both eradication of pathogens and control of the associated immune response.
Features
- Active Ingredients: Ciprofloxacin hydrochloride 0.3% (as base) and dexamethasone 0.1%
- Pharmacological Class: Antibacterial/Corticosteroid combination
- Presentation: Sterile suspension in 5 mL or 10 mL dropper bottles
- pH: Adjusted to approximately 5.0 to facilitate ocular comfort
- Preservative: Benzalkonium chloride 0.01%
- Mechanism: Bactericidal action via inhibition of bacterial DNA gyrase and topoisomerase IV; anti-inflammatory via inhibition of multiple inflammatory cytokines
Benefits
- Provides broad-spectrum coverage against common Gram-positive and Gram-negative ocular pathogens, including Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae, and Pseudomonas aeruginosa
- Rapidly reduces inflammation, pain, redness, and discomfort associated with bacterial eye infections
- Decreases risk of corneal scarring and visual impairment by controlling excessive inflammatory response
- Convenient twice-daily dosing regimen supports patient adherence to treatment
- Formulated as a uniform suspension for consistent dosing and efficacy throughout treatment course
- Helps shorten the duration of symptomatic infection and promotes faster clinical resolution
Common use
Ciprodex Ophthalmic Solution is indicated for the treatment of superficial ocular infections, such as bacterial conjunctivitis, caused by susceptible strains of organisms. It is also used in cases where corticosteroid use is indicated for inflammatory conditions and where a superficial bacterial ocular infection or a risk of bacterial ocular infection exists. Its use should be reserved for cases where the anti-inflammatory action of dexamethasone is deemed necessary to reduce swelling, redness, and discomfort.
Dosage and direction
The recommended dosage for Ciprodex Ophthalmic Solution is one to two drops instilled into the conjunctival sac of the affected eye(s) every 12 hours, for 7 days, or as directed by a healthcare professional. Before administration, the bottle should be shaken well to ensure a homogeneous suspension. To avoid contamination, care should be taken not to touch the dropper tip to any surface, including the eye or fingers. If more than one topical ophthalmic drug is being used, the solutions should be administered at least 5 minutes apart.
Precautions
- Prolonged use may result in overgrowth of non-susceptible organisms, including fungi. If superinfection occurs, appropriate therapy should be initiated.
- Use with caution in patients with a history of sensitivity to any component of the preparation.
- Corneal perforation has been reported in the use of topical steroids in diseases causing thinning of the cornea or sclera.
- Intraocular pressure should be routinely monitored even though it may be difficult in children and uncooperative patients.
- Not for injection or direct introduction into the anterior chamber of the eye.
- Patients should be advised not to wear contact lenses if they have signs and symptoms of ocular infection.
Contraindications
Ciprodex Ophthalmic Solution is contraindicated in patients with known hypersensitivity to any of its components, to other quinolones, or to any of the other ingredients in the formulation. It is also contraindicated in most viral diseases of the cornea and conjunctiva, including epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, and varicella, and also in mycobacterial infection of the eye and fungal diseases of ocular structures.
Possible side effect
Common adverse reactions occurring in approximately 1-5% of patients include conjunctival hyperemia, blurred vision, corneal deposits, ocular irritation, ocular pain, and taste disturbance. Less frequently, allergic reactions, eyelid edema, photophobia, and tearing may occur. As with other antibiotic-steroid combinations, prolonged use may lead to secondary infection, increased intraocular pressure, glaucoma, optic nerve damage, cataract formation, and delayed wound healing.
Drug interaction
Although systemic absorption is low following topical ocular administration, interactions are possible. Concurrent use with other corticosteroid-containing products may increase the risk of systemic steroid effects. No specific drug interaction studies have been conducted with Ciprodex. However, caution is advised when using with other medications that are known to prolong the QT interval. Patients should inform their physician of all medications they are taking.
Missed dose
If a dose is missed, it should be administered as soon as possible. However, if it is almost time for the next dose, the missed dose should be skipped, and the regular dosing schedule resumed. Doubling the dose is not recommended.
Overdose
Topical overdose of Ciprodex Ophthalmic Solution is unlikely to produce significant systemic effects due to limited absorption. However, the eye may be flushed with warm tap water in case of accidental excessive application. In case of accidental ingestion, symptomatic and supportive measures should be taken. There is no specific antidote.
Storage
Store at controlled room temperature 15°-30°C (59°-86°F). Protect from light and freezing. Keep the bottle tightly closed when not in use. Discard any unused portion 28 days after opening to avoid contamination and reduced efficacy.
Disclaimer
This information is intended for medical professionals and does not replace professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read in this product card.
Reviews
(Clinical summary based on prescribing information and studies) In clinical trials, Ciprodex Ophthalmic Solution demonstrated high clinical cure rates and bacterial eradication in patients with bacterial conjunctivitis. The combination of ciprofloxacin and dexamethasone was shown to be more effective than either component alone in reducing inflammatory signs and symptoms. Physicians report satisfactory results in cases requiring both anti-infective and anti-inflammatory action, with a favorable safety profile consistent with topical ophthalmic preparations.