Diamox: Effective Acetazolamide Therapy for Glaucoma & Altitude Sickness
| Product dosage: 250mg | |||
|---|---|---|---|
| Package (num) | Per pill | Price | Buy |
| 60 | $1.00 | $60.15 (0%) | 🛒 Add to cart |
| 90 | $0.90 | $90.23 $81.21 (10%) | 🛒 Add to cart |
| 120 | $0.70 | $120.31 $84.21 (30%) | 🛒 Add to cart |
| 180 | $0.60 | $180.46 $108.28 (40%) | 🛒 Add to cart |
| 270 | $0.50 | $270.69 $135.34 (50%) | 🛒 Add to cart |
| 360 | $0.40
Best per pill | $360.92 $144.37 (60%) | 🛒 Add to cart |
Synonyms | |||
Diamox, known generically as acetazolamide, is a carbonic anhydrase inhibitor prescribed for managing specific medical conditions such as glaucoma, certain types of seizures, edema due to congestive heart failure, and altitude sickness. It works by reducing the production of fluid in the eye and promoting diuresis, thereby alleviating pressure and associated symptoms. This medication is available in tablet and extended-release capsule forms, requiring precise medical supervision for optimal therapeutic outcomes.
Features
- Active ingredient: Acetazolamide
- Available formulations: 125 mg and 250 mg tablets; 500 mg extended-release capsules
- Mechanism of action: Carbonic anhydrase inhibition
- Prescription-only medication
- Suitable for adults and pediatric use under medical guidance
Benefits
- Reduces intraocular pressure effectively in glaucoma patients, helping preserve vision.
- Prevents and treats symptoms of acute mountain sickness, enabling safer high-altitude activities.
- Assists in managing certain types of epileptic seizures as adjunctive therapy.
- Promotes diuresis to alleviate fluid retention in conditions like heart failure.
- May aid in correcting metabolic alkalosis in clinical settings.
- Supports faster acclimatization to high altitudes with prophylactic use.
Common use
Diamox is commonly prescribed for the management of open-angle glaucoma, secondary glaucoma, and preoperatively in acute angle-closure glaucoma to lower intraocular pressure. It is also utilized as an adjunctive treatment for certain seizure disorders, such as absence seizures or mixed seizure types. Additionally, it is indicated for the prevention and treatment of acute mountain sickness, reducing symptoms like headache, nausea, and dizziness. Off-label uses may include the management of idiopathic intracranial hypertension and metabolic alkalosis.
Dosage and direction
Dosage must be individualized based on the condition being treated, patient response, and tolerance. For glaucoma: adults may take 250 mg to 1 g daily in divided doses. For altitude sickness: 125 mg to 250 mg every 8 to 12 hours, starting 24 to 48 hours before ascent and continuing for 48 hours after reaching the desired altitude. For seizures: 8 to 30 mg/kg per day in divided doses for pediatric patients, and similar weight-based or fixed dosing in adults. Extended-release capsules should be swallowed whole and not crushed or chewed. Always follow the specific instructions provided by the healthcare provider.
Precautions
Patients should inform their healthcare provider of any history of kidney disease, liver impairment, adrenal gland failure, or electrolyte imbalances. Regular monitoring of blood counts, electrolyte levels, and renal function may be necessary during treatment. Use with caution in patients with respiratory acidosis or chronic obstructive pulmonary disease (COPD). Avoid prolonged exposure to sunlight, as Diamox may increase sensitivity, leading to sunburn. Pregnant or breastfeeding women should use only if clearly needed and under medical supervision.
Contraindications
Diamox is contraindicated in patients with known hypersensitivity to acetazolamide or sulfonamide-derived drugs. It should not be used in those with severe renal or hepatic dysfunction, low levels of sodium or potassium, adrenal failure, or hyperchloremic acidosis. Concurrent use with high-dose aspirin is contraindicated due to the risk of metabolic acidosis and other complications.
Possible side effect
Common side effects may include numbness or tingling in the extremities, loss of appetite, taste alteration, nausea, vomiting, diarrhea, drowsiness, and increased urination. Less frequently, patients may experience blurred vision, confusion, hearing dysfunction, or rash. Serious side effects such as blood dyscrasias, Stevens-Johnson syndrome, or severe metabolic acidosis are rare but require immediate medical attention.
Drug interaction
Diamox may interact with other medications, including but not limited to: high-dose salicylates (increasing risk of toxicity), other diuretics (potentiating electrolyte imbalance), anticonvulsants like phenytoin (altering efficacy), and drugs that affect acid-base balance. It may enhance the effects of amphetamines, quinidine, or lithium, and decrease the effectiveness of methenamine. Always inform the healthcare provider of all medications, supplements, and herbal products being taken.
Missed dose
If a dose is missed, take it as soon as remembered unless it is almost time for the next scheduled dose. In that case, skip the missed dose and resume the regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects.
Overdose
Symptoms of overdose may include electrolyte imbalance, metabolic acidosis, drowsiness, confusion, and in severe cases, convulsions or coma. In the event of suspected overdose, seek immediate medical attention or contact a poison control center. Treatment is supportive and may include correction of electrolyte disturbances and acid-base balance.
Storage
Store Diamox at room temperature, between 15°C to 30°C (59°F to 86°F), in a tightly closed container away from light, moisture, and heat. Keep out of reach of children and pets. Do not use beyond the expiration date printed on the packaging.
Disclaimer
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider for personalized recommendations and before starting or altering any medication regimen. Do not disregard professional medical advice or delay seeking it based on content provided here.
Reviews
Clinical studies and patient reports generally affirm the efficacy of Diamox in reducing intraocular pressure and managing altitude sickness. Many users note significant symptom relief, though some report side effects like paresthesia or gastrointestinal discomfort. Adherence to prescribed dosing and regular follow-up with a healthcare provider are emphasized for optimal results and minimal adverse effects. Individual experiences may vary.