Levlen is a trusted combined oral contraceptive pill, meticulously formulated with ethinylestradiol and levonorgestrel to provide highly effective pregnancy prevention. It offers a reliable, reversible method of birth control for women, working through a dual mechanism to inhibit ovulation and alter cervical mucus. This medication is designed for daily oral administration as part of a 28-day cyclic regimen, balancing hormonal delivery for both efficacy and tolerability. Approved for use under medical guidance, it represents a cornerstone in modern contraceptive options, supporting family planning and reproductive autonomy.

Features

• Contains ethinylestradiol 30 mcg and levonorgestrel 150 mcg per active tablet
• Packaged in a 28-day blister pack (21 active tablets, 7 placebo tablets)
• Monophasic formulation ensuring consistent hormone levels throughout the cycle
• Small, easy-to-swallow tablets with clear day markings for adherence
• Manufactured under strict pharmaceutical quality standards

Benefits

• Over 99% effective at preventing pregnancy when taken correctly
• May result in lighter, less painful, and more regular menstrual periods
• Offers non-contraceptive benefits such as reduced risk of ovarian cysts and ectopic pregnancy
• Provides reversible contraception, allowing for future fertility upon discontinuation
• Can improve acne in some users due to anti-androgenic effects of levonorgestrel
• Supports personal family planning goals with a discrete, user-controlled method

Common use

Levlen is primarily prescribed for the prevention of pregnancy in women of reproductive age. It is suitable for those seeking a reliable, daily oral contraceptive method. Additionally, healthcare providers may recommend it for the management of moderate acne in females at least 15 years old who have no known contraindications to hormonal contraception, desire contraception, have achieved menarche, and are unresponsive to topical acne treatments.

Dosage and direction

Take one tablet daily at approximately the same time each day, with or without food. Follow the directional arrows on the blister pack, beginning with the first active tablet (labeled “Start” or “Day 1”). After taking all 21 active tablets, take one placebo tablet daily for 7 days. Menstruation usually begins during the placebo week. Start a new pack the day after finishing the placebo tablets, regardless of whether menstruation has ended. For specific starting instructions (e.g., Sunday start or first-day start), follow healthcare provider guidance.

Precautions

• Not protective against HIV infection or other sexually transmitted diseases
• Cigarette smoking increases the risk of serious cardiovascular side effects, especially in women over 35 years old; smoking is strongly discouraged
• May influence glucose tolerance; monitor closely in diabetic patients
• Periodic medical examinations are recommended, including blood pressure checks and assessments for cervical and breast changes
• Use with caution in patients with conditions that might be aggravated by fluid retention
• Hormonal contraceptives may affect certain endocrine and liver function tests; inform laboratory personnel of Levlen use

Contraindications

• Thrombophlebitis or thromboembolic disorders, past or present
• Known or suspected carcinoma of the breast or estrogen-dependent neoplasia
• Undiagnosed abnormal genital bleeding
• Known or suspected pregnancy
• Active liver disease or history of cholestatic jaundice with prior pill use
• Cerebral vascular or coronary artery disease
• Heavy smoking (≥15 cigarettes/day) and over age 35
• Hypertension with vascular involvement
• Diabetes with vascular involvement
• Headaches with focal neurological symptoms
• Major surgery with prolonged immobilization
• Hypersensitivity to any component of Levlen

Possible side effects

Common side effects may include nausea, vomiting, headache, bloating, breast tenderness, weight change, and mood changes. These often subside after the first few cycles. Less frequently, users may experience melasma, change in libido, vaginal candidiasis, or contact lens intolerance. Serious side effects requiring immediate medical attention include sudden severe headache, chest pain, shortness of breath, severe leg pain, jaundice, or sudden vision changes.

Drug interaction

Levlen may interact with drugs that induce hepatic enzymes, potentially reducing contraceptive efficacy and increasing breakthrough bleeding. Such drugs include rifampin, barbiturates, carbamazepine, phenytoin, primidone, topiramate, and certain HIV medications. Broad-spectrum antibiotics like ampicillin and tetracyclines may also diminish effectiveness. Conversely, Levlen may alter the metabolism of cyclosporine, theophylline, and corticosteroids. Always inform healthcare providers of all concomitant medications.

Missed dose

If one active tablet is missed (24–48 hours late), take it as soon as remembered and the next tablet at the regular time. If two consecutive active tablets are missed in weeks 1 or 2, take two tablets as soon as remembered and two the next day, then resume regular schedule; use backup contraception for 7 days. If two tablets are missed in week 3 or three or more consecutive tablets are missed at any time, discard the current pack and start a new pack the same day; use backup contraception for 7 days. If placebo tablets are missed, discard them and resume regular schedule.

Overdose

Serious ill effects have not been reported following acute overdose of oral contraceptives. Overdosage may cause nausea, vomiting, and withdrawal bleeding. In case of suspected overdose, seek medical attention or contact a Poison Control Center. There is no specific antidote; treatment should be symptomatic and supportive.

Storage

Store at room temperature (20–25°C or 68–77°F), with excursions permitted between 15–30°C (59–86°F). Protect from light and moisture. Keep out of reach of children and pets. Do not use after the expiration date printed on the packaging.

Disclaimer

This information is for educational purposes only and does not replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider for personalized guidance regarding contraception, health conditions, and medication use. Individual results and experiences may vary.

Reviews

Clinical studies and user experiences generally report high satisfaction with Levlen for its efficacy and cycle regulation. Many users appreciate the predictable menstruation and minimal side effects after the initial adjustment period. Some note improvement in acne and reduced menstrual cramps. As with all hormonal contraceptives, individual responses vary, and a healthcare provider can help determine if Levlen is appropriate based on medical history and lifestyle.