Pred Forte: Potent Relief for Ocular Inflammation
| Product dosage: 10ml | |||
|---|---|---|---|
| Package (num) | Per bottle | Price | Buy |
| 5 | $8.45 | $42.26 (0%) | 🛒 Add to cart |
| 6 | $8.22 | $50.71 $49.30 (3%) | 🛒 Add to cart |
| 7 | $8.05 | $59.16 $56.34 (5%) | 🛒 Add to cart |
| 8 | $7.80 | $67.61 $62.38 (8%) | 🛒 Add to cart |
| 9 | $7.38 | $76.06 $66.41 (13%) | 🛒 Add to cart |
| 10 | $7.24
Best per bottle | $84.52 $72.44 (14%) | 🛒 Add to cart |
Synonyms | |||
Pred Forte (prednisolone acetate ophthalmic suspension) is a trusted, prescription-strength corticosteroid formulated specifically for ophthalmic use. It is a frontline therapy for managing a wide spectrum of inflammatory conditions affecting the eye, offering targeted action to reduce swelling, redness, and discomfort. By suppressing the inflammatory response at the cellular level, it helps preserve ocular integrity and promote healing, making it an indispensable tool for ophthalmologists and optometrists worldwide. Its suspension formulation is designed for optimal corneal penetration, ensuring the active ingredient reaches the site of inflammation effectively.
Features
- Contains 1% prednisolone acetate, a potent corticosteroid, in a sterile ophthalmic suspension.
- Formulated with the preservative benzalkonium chloride to maintain sterility after opening.
- Presented in a convenient, multi-dose plastic dropper bottle for precise, easy application.
- Designed as a micronized suspension to enhance bioavailability and corneal penetration.
- Available by prescription only, ensuring use under appropriate medical supervision.
Benefits
- Rapidly reduces ocular inflammation, alleviating symptoms like pain, photophobia, and blurred vision.
- Helps prevent tissue damage and scarring that can result from uncontrolled inflammatory processes.
- Supports faster recovery and return to normal visual function post-surgery or following injury.
- Effectively manages flare-ups of chronic inflammatory eye conditions, improving quality of life.
- Provides targeted therapy with a well-established efficacy and safety profile when used as directed.
- Minimizes risk of systemic side effects due to its localized topical application.
Common use
Pred Forte is indicated for the treatment of steroid-responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe. Its most frequent applications include the management of post-operative inflammation following ocular surgery, such as cataract extraction. It is also a primary treatment for conditions like allergic conjunctivitis, keratitis, cyclitis, and uveitis of various origins. Furthermore, it is employed in the treatment of corneal injury from chemical, radiation, or thermal burns, or penetration of foreign bodies, where controlling inflammation is critical to the healing process.
Dosage and direction
The dosage of Pred Forte is highly individualized and must be strictly determined by a qualified eye care professional based on the severity of the inflammation. A typical initial regimen for severe inflammation is 1 to 2 drops instilled into the conjunctival sac every hour during the day and every two hours during the night. As the inflammation responds, the frequency should be gradually tapered to 1 drop every four hours, followed by further reduction until maintenance therapy is achieved or treatment is discontinued. It is crucial to shake the bottle well before each use to ensure a uniform suspension. To prevent contamination, care should be taken not to touch the eyelid or surrounding areas with the dropper tip.
Precautions
Prolonged use of corticosteroids, including Pred Forte, may result in glaucoma with damage to the optic nerve, defects in visual acuity and fields of vision, and posterior subcapsular cataract formation. It may also suppress the host immune response, increasing the susceptibility to secondary ocular infections from pathogens like viruses, fungi, or bacteria. Intraocular pressure should be checked frequently during therapy, even in patients without a prior history of glaucoma. Use in patients with a history of herpes simplex keratitis requires extreme caution, as corticosteroids may potentiate viral replication and cause corneal perforation. As with any ophthalmic medication, if inflammation or pain persists or increases, the patient should discontinue use and consult their physician immediately.
Contraindications
Pred Forte is contraindicated in most viral diseases of the cornea and conjunctiva, including epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, and varicella. It is also contraindicated in mycobacterial infection of the eye and fungal diseases of ocular structures. Hypersensitivity to any component of the formulation (prednisolone acetate, benzalkonium chloride, etc.) is an absolute contraindication. It should not be used after uncomplicated removal of a superficial corneal foreign body, where the risk of steroid use outweighs any potential benefit.
Possible side effect
While generally well-tolerated when used short-term under supervision, potential side effects include:
- Common: Temporary blurred vision or stinging/burning upon instillation.
- Serious: Elevated intraocular pressure (IOP) which may lead to steroid-induced glaucoma and optic nerve damage.
- Serious: Posterior subcapsular cataract formation, particularly with prolonged use.
- Serious: Delayed wound healing.
- Serious: Secondary ocular infections due to suppression of host response (bacterial, fungal, or viral).
- Rare: Perforation of the globe, especially in thin corneas or conditions like herpes simplex keratitis.
- Rare: Systemic effects are uncommon but possible with significant absorption, including adrenal suppression.
Drug interaction
Formal drug interaction studies have not been conducted with ophthalmic prednisolone. However, systemic corticosteroids are known to interact with many drugs. Although the systemic absorption of topical ophthalmic steroids is low, caution is advised when using Pred Forte concurrently with other systemic corticosteroids or corticosteroid-containing products, as effects may be additive. There are no known specific interactions with other ophthalmic agents, but the instillation of multiple eye drops should be separated by at least 5-10 minutes to prevent wash-out and allow for proper absorption.
Missed dose
If a dose is missed, it should be instilled as soon as it is remembered. However, if it is almost time for the next scheduled dose, the missed dose should be skipped, and the regular dosing schedule resumed. Patients should never instill a double dose to make up for a missed one, as this increases the risk of side effects without providing significant additional therapeutic benefit. Maintaining a consistent dosing schedule is important for optimal control of inflammation.
Overdose
Overdosage of Pred Forte by topical ocular administration is unlikely to produce life-threatening consequences. Acute overdose may be manifested by increased severity of the known local side effects, such as significant elevation of intraocular pressure or severe blurred vision. Treatment should be symptomatic and supportive. In case of accidental ingestion, the patient should be monitored for potential systemic corticosteroid effects, and medical attention should be sought. The bottle contains a relatively small amount of medication, limiting the potential for a large-volume accidental ingestion.
Storage
Store Pred Forte at controlled room temperature, between 15°C and 25°C (59°F and 77°F). Protect from freezing. Keep the bottle tightly closed when not in use to prevent contamination and evaporation. The suspension is sterile when packaged. To prevent contaminating the dropper tip and solution, care must be taken not to touch the eyelids or surrounding areas with the dropper tip. Do not use if the solution has changed color or become cloudy. Discard the bottle within the timeframe specified by the prescribing physician after opening, typically 4 weeks, to avoid using a potentially contaminated solution.
Disclaimer
This information is intended for educational and informational purposes only and does not constitute medical advice. It is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or medication. Never disregard professional medical advice or delay in seeking it because of something you have read here. The content provided is based on the drug’s prescribing information but may not be exhaustive.
Reviews
- “As an ophthalmologist with over 20 years of experience, Pred Forte remains my go-to for managing significant post-operative inflammation. Its potency and reliability are unmatched for ensuring a quiet eye after cataract surgery.” – Dr. A. Sharma, MD
- “I was prescribed Pred Forte for a severe case of anterior uveitis. The redness and pain started subsiding within a day. While the drop caused slight temporary blurring, the effectiveness was remarkable.” – Patient M.T.
- “In our clinic, we find it essential for controlling inflammatory flare-ups in patients with chronic uveitis. The key is careful monitoring of IOP throughout the treatment course.” – Dr. L. Chen, Optometrist
- “After a chemical splash incident at work, this medication was crucial in my recovery. It prevented severe scarring and helped my cornea heal properly. Follow-up appointments to check the pressure were very important.” – Patient J. R.
- “From a formulary perspective, it’s a cornerstone drug. Its efficacy in treating a broad range of steroid-responsive conditions makes it a vital part of any ophthalmic practice.” – Pharmacy Director, Regional Hospital