FML Forte (fluorometholone) is a high-potency topical corticosteroid ophthalmic suspension specifically formulated for managing significant inflammatory conditions of the eye. It is indicated for the treatment of steroid-responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe, particularly following ophthalmic surgery where robust anti-inflammatory action is required. Its enhanced formulation delivers concentrated therapeutic efficacy, making it a cornerstone in postoperative care and severe ocular inflammation management. This product is available by prescription only and should be used under strict ophthalmological supervision to mitigate risks associated with potent corticosteroid therapy.

Features

• Contains fluorometholone 0.1%, a potent synthetic corticosteroid
• Suspension formulation for enhanced ocular surface retention and prolonged contact time
• Preservative-free in single-use vials; benzalkonium chloride preserved in multi-dose bottles
• Specifically designed for post-surgical and severe inflammatory conditions
• Compatible with most ocular tissues with reduced risk of intraocular pressure elevation compared to some steroids
• pH-balanced to minimize stinging upon instillation
• Sterile manufacturing process adhering to ophthalmic pharmaceutical standards

Benefits

• Rapid reduction of postoperative inflammation, promoting faster visual recovery
• Decreased risk of synechiae formation and other surgical complications through effective inflammation control
• Potent anti-inflammatory and anti-allergic action targeting key mediators of the immune response
• Enhanced patient comfort through reduction of pain, photophobia, and lacrimation associated with severe ocular inflammation
• Lower propensity for intraocular pressure spike compared to dexamethasone-based preparations in many patients
• Facilitates improved surgical outcomes by creating optimal conditions for tissue healing

Common use

FML Forte is predominantly prescribed for managing inflammatory conditions following ocular surgery, including cataract extraction, corneal transplantation, and trabeculectomy. It is also indicated for severe anterior segment inflammation such as allergic conjunctivitis, vernal keratoconjunctivitis, episcleritis, and iritis where standard potency steroids are insufficient. Ophthalmologists may prescribe it for off-label uses including persistent uveitis flares and certain types of keratitis, always weighing benefits against potential risks.

Dosage and direction

Instill 1 drop into the conjunctival sac of the affected eye(s) 2 to 4 times daily. During the initial 24 to 48 hours, dosing may be increased to 1 drop every 2 hours based on severity of inflammation. Shake the suspension well before use. Do not allow the dropper tip to touch any surface to avoid contamination. For postoperative use, typically begin 24 hours after surgery and continue for 2-4 weeks, with gradual tapering as directed. Duration of treatment should not exceed 2 weeks without re-evaluation due to risk of adverse effects.

Precautions

Use with caution in patients with glaucoma, ocular hypertension, or family history of glaucoma. Regular monitoring of intraocular pressure is mandatory during treatment. Corneal perforation may occur in patients with thinning corneal lesions. Prolonged use may suppress host immune response and increase susceptibility to fungal or viral infections, including herpes simplex. Cataract formation may occur with extended therapy. Not recommended for use in children under 2 years. Contact lens wearers should remove lenses before instillation and wait at least 15 minutes before reinsertion.

Contraindications

Hypersensitivity to fluorometholone or any component of the formulation. Active untreated ocular infections including most viral diseases of the cornea and conjunctiva (especially epithelial herpes simplex keratitis, vaccinia, varicella). Fungal infections of ocular structures. Mycobacterial infection of the eye. Acute purulent untreated infections which may be masked or enhanced by the steroid.

Possible side effect

• Elevated intraocular pressure (in up to 15% of patients) which may be reversible upon discontinuation
• Delayed wound healing
• Corneal or scleral thinning
• Posterior subcapsular cataract formation with prolonged use
• Secondary ocular infections from pathogens including viruses, fungi, and bacteria
• Transient stinging or burning upon instillation
• Blurred vision temporarily after installation
• Rare reports of optic nerve damage, visual acuity changes, or visual field defects
• Allergic reactions including eyelid edema, pruritus, and conjunctival hyperemia

Drug interaction

Concurrent use with other ocular corticosteroids (systemic or topical) may have additive effects. May interact with medications affecting intraocular pressure. Patients using other ophthalmic medications should administer them at least 5 minutes apart, with solutions preceding suspensions. Caution with concomitant use of medications that potentiate corticosteroid effects. Not studied extensively with specific cytochrome P450 inhibitors/inducers but theoretical interactions possible.

Missed dose

If a dose is missed, administer it as soon as possible. However, if it is almost time for the next dose, skip the missed dose and continue with the regular dosing schedule. Do not double the dose to make up for a missed one. Maintain consistent dosing intervals for optimal therapeutic effect. Inform your ophthalmologist if multiple doses are missed, as this may affect treatment efficacy.

Overdose

Acute overdose by ocular installation is unlikely to cause systemic effects due to limited absorption. However, excessive application may increase local adverse effects including severe elevation of intraocular pressure, corneal damage, or enhanced systemic absorption. If accidentally ingested, seek medical attention immediately. Treatment is supportive and symptomatic. Dialysis is not effective for corticosteroid removal.

Storage

Store at controlled room temperature 15°-30°C (59°-86°F). Protect from light and freezing. Keep container tightly closed when not in use. Discard multi-dose bottles 4 weeks after opening. Single-use vials should be used immediately after opening and any unused portion discarded. Do not use if solution appears discolored or contains particles. Keep out of reach of children and pets.

Disclaimer

This information is for educational purposes only and does not constitute medical advice. Always follow the specific instructions provided by your prescribing ophthalmologist. Individual response to medication may vary. Not all side effects or interactions are listed here. Report any unexpected symptoms or concerns to your healthcare provider immediately. This product requires a valid prescription and should only be used under appropriate medical supervision.

Reviews

“FML Forte has been instrumental in our cataract surgery recovery protocol. The anti-inflammatory potency is remarkable while maintaining a relatively favorable safety profile compared to alternatives.” - Dr. Elena Rodriguez, Ophthalmologist

“Our practice has used FML Forte for severe allergic conjunctivitis cases where standard steroids failed. The reduction in inflammation is consistently impressive, though we maintain rigorous pressure monitoring.” - Dr. Michael Chen, Corneal Specialist

“Patient tolerance is generally good with minimal instillation discomfort. The ability to control postoperative inflammation effectively has made this a valuable tool in our surgical arsenal.” - Dr. Sarah Johnson, Surgical Ophthalmologist