Podowart is a physician-formulated topical solution designed for the targeted removal of common warts and verrucae. Its active ingredient, podophyllotoxin, is derived from natural sources and works by inhibiting the growth of affected tissue, leading to the gradual and controlled destruction of the wart. This treatment is valued in dermatological practice for its precision, efficacy, and suitability for patient-administered use, offering a reliable alternative to more invasive procedures. Proper application ensures minimal impact on surrounding healthy skin, making it a preferred choice for both clinicians and patients seeking effective wart management.

Features

• Contains 0.5% podophyllotoxin as the active pharmaceutical ingredient
• Available in a convenient liquid solution form with a precise applicator
• Formulated for topical use only, ensuring localized treatment
• Packaged in amber glass bottles to protect stability and potency
• Clinically tested for safety and efficacy in wart removal
• Requires no prescription in some regions, though professional consultation is advised

Benefits

• Effectively targets and destroys wart tissue through antimitotic action
• Reduces the need for surgical interventions such as cryotherapy or excision
• Allows for precise application, minimizing damage to surrounding healthy skin
• Supports patient self-management with clear, easy-to-follow instructions
• Provides visible results within weeks with consistent use
• Helps prevent the spread of warts to other areas or individuals

Common use

Podowart is primarily indicated for the treatment of external genital warts (condylomata acuminata) and common non-genital warts caused by the human papillomavirus (HPV). It is suitable for adults and may be used under medical supervision for immunocompetent patients. It is not intended for mucosal surfaces, facial warts, or warts with hair growth, and should be avoided in cases of bleeding, irritated, or infected skin.

Dosage and direction

Apply Podowart twice daily (morning and evening) for 3 consecutive days, followed by a 4-day treatment-free interval. This cycle may be repeated for up to 4 weeks or as directed by a healthcare provider. Using the supplied applicator, apply a thin layer solely to the wart, ensuring the solution does not contact surrounding skin. Wash hands thoroughly before and after application. Do not exceed recommended frequency or duration of use.

Precautions

• For external use only; avoid contact with eyes, mouth, nostrils, and broken skin.
• Do not apply to large areas or multiple warts simultaneously without medical advice.
• Use with caution in patients with diabetes or circulatory disorders.
• Discontinue use if excessive irritation, pain, or swelling occurs.
• Keep out of reach of children and pets.
• Pregnancy and breastfeeding: Consult a physician before use.

Contraindications

Podowart is contraindicated in patients with known hypersensitivity to podophyllotoxin or any excipients in the formulation. It should not be used on birthmarks, moles, or undiagnosed skin growths. Avoid use in patients with bleeding disorders or compromised immune systems (e.g., HIV/AIDS, organ transplant recipients) unless under direct medical supervision. Do not use on children under 12 years of age.

Possible side effect

Common side effects may include localized redness, burning, itching, or mild pain at the application site. These are generally transient and resolve after discontinuation. Less frequently, skin erosion, inflammation, or blistering may occur. Systemic absorption is rare but could lead to nausea, vomiting, or neurological symptoms if misapplied or overused. Seek medical attention if severe reactions develop.

Drug interaction

No significant drug interactions have been widely reported with topical podophyllotoxin. However, concurrent use with other topical agents (e.g., corticosteroids, acids, or abrasive preparations) may increase skin irritation or compromise treatment efficacy. Inform your healthcare provider of all medications, including over-the-counter products and supplements, prior to use.

Missed dose

If a dose is missed, apply it as soon as remembered, unless it is nearly time for the next scheduled application. Do not double the dose to make up for a missed one. Resume the regular dosing schedule and continue the treatment cycle as prescribed.

Overdose

Overapplication or accidental ingestion may lead to severe local reactions or systemic toxicity, including nausea, vomiting, diarrhea, CNS effects, or bone marrow suppression. In case of suspected overdose, remove any residual product, wash the area with soap and water, and seek immediate medical attention or contact a poison control center.

Storage

Store Podowart at room temperature (15–30°C), in its original container, protected from light and moisture. Do not freeze. Keep the bottle tightly closed when not in use. Discard any unused product 90 days after first opening or by the expiration date, whichever comes first.

Disclaimer

This information is intended for educational purposes and does not replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before using any medication, especially if you have underlying health conditions or concerns about suitability. Use strictly as directed; off-label use is not recommended.

Reviews

Clinical studies and user reports indicate high rates of complete wart clearance with Podowart when used as directed. Patients appreciate its convenience and effectiveness, though some note mild transient irritation. Dermatologists often recommend it as a first-line topical treatment for appropriate candidates.