Voveran SR is a prescription medication containing diclofenac sodium, a potent nonsteroidal anti-inflammatory drug (NSAID) formulated for sustained release. It is specifically designed to manage moderate to severe pain and inflammation associated with various musculoskeletal and arthritic conditions. By providing continuous therapeutic effect over an extended period, it supports improved mobility and quality of life for patients requiring long-term analgesic and anti-inflammatory therapy.

Features

• Active ingredient: Diclofenac sodium 100 mg
• Pharmaceutical form: Sustained-release tablet
• Mechanism: Cyclooxygenase (COX) inhibition, reducing prostaglandin synthesis
• Release profile: Gradual and prolonged absorption over 12 hours
• Coating: Enteric-coated to minimize gastric irritation
• Packaging: Blister strips, typically 10 tablets per strip

Benefits

• Provides consistent, around-the-clock relief from pain and swelling
• Reduces stiffness and improves joint mobility in arthritic conditions
• Enables fewer daily doses compared to immediate-release formulations
• Supports long-term management of chronic inflammatory disorders
• Helps restore functional ability and daily activity levels
• Minimizes peak-trough fluctuations in plasma concentration

Common use

Voveran SR is commonly prescribed for the management of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and other inflammatory joint diseases. It is also used for acute musculoskeletal disorders such as low back pain, soft tissue injuries, and post-operative pain where prolonged anti-inflammatory and analgesic effects are required.

Dosage and direction

The usual adult dose is one tablet (100 mg) once daily, taken whole with food or milk to reduce gastrointestinal discomfort. Tablets should not be crushed, chewed, or broken as this disrupts the sustained-release mechanism. Dosage may be adjusted based on individual response and severity of symptoms, not exceeding 150 mg daily in divided doses. Treatment duration should be the shortest possible consistent with therapeutic goals.

Precautions

Use with caution in elderly patients, those with a history of gastrointestinal disorders, hypertension, cardiac impairment, or renal dysfunction. Monitor renal function during long-term therapy. Avoid concomitant use with other NSAIDs. Patients should be advised to report any signs of gastrointestinal bleeding, skin reactions, or visual disturbances. Use the lowest effective dose for the shortest duration necessary.

Contraindications

Hypersensitivity to diclofenac, aspirin, or other NSAIDs. Active peptic ulcer disease or history of recurrent ulceration/bleeding. Severe heart failure, hepatic failure, or renal failure. Third trimester of pregnancy. Established coronary artery bypass graft (CABG) surgery. History of asthma, urticaria, or allergic-type reactions after taking NSAIDs.

Possible side effect

Common: Dyspepsia, nausea, abdominal pain, diarrhea, headache, dizziness. Less common: Elevation of liver enzymes, fluid retention, hypertension, skin rash, tinnitus. Rare: Gastrointestinal bleeding or perforation, severe skin reactions, anaphylaxis, hepatitis, pancreatitis, renal impairment, congestive heart failure. Patients should seek immediate medical attention for signs of allergic reactions or gastrointestinal bleeding.

Drug interaction

Significant interactions with: Anticoagulants (increased bleeding risk), ACE inhibitors/ARBs (reduced antihypertensive effect), diuretics (reduced efficacy, risk of renal impairment), lithium (increased lithium levels), methotrexate (increased toxicity), cyclosporine (increased nephrotoxicity), other NSAIDs (additive toxicity), SSRIs (increased bleeding risk). Consult healthcare provider before starting any new medication.

Missed dose

If a dose is missed, take it as soon as remembered unless it is almost time for the next scheduled dose. Do not double the dose to make up for a missed one. Maintain regular dosing schedule to ensure consistent therapeutic levels.

Overdose

Symptoms may include nausea, vomiting, epigastric pain, gastrointestinal bleeding, drowsiness, dizziness, tinnitus, convulsions, or respiratory depression. In case of suspected overdose, seek immediate medical attention. Treatment is supportive and symptomatic; gastric lavage and activated charcoal may be considered if presented early. Hemodialysis is not effective due to high protein binding.

Storage

Store at room temperature (15-30°C) in original packaging, protected from light and moisture. Keep out of reach of children. Do not use after expiration date printed on packaging.

Disclaimer

This information is for educational purposes only and does not replace professional medical advice. Always consult a healthcare provider before starting or changing medication. Proper diagnosis and individualized treatment planning are essential for safe and effective use. Do not self-medicate or share prescription medications with others.

Reviews

Clinical studies demonstrate Voveran SR’s efficacy in reducing pain scores and improving physical function in arthritis patients. Many patients report significant improvement in daily activities and quality of life. Healthcare professionals appreciate its once-daily dosing convenience and consistent therapeutic effect. However, individual responses may vary, and careful monitoring is recommended, particularly in long-term use.